Size at birth and glucose intolerance in a relatively genetically homogeneous, high–birth weight population

Size at birth and glucose intolerance in a relatively genetically homogeneous, high-birth weight population.

BACKGROUND The results of epidemiologic studies have linked birth size to adult glucose intolerance. OBJECTIVE We investigated this association in a genetically homogeneous population with higher birth weights and a lower prevalence of type 2 diabetes than previously studied. DESIGN The subjects were 2362 men and 2286 women aged 33-65 y. Size at birth was obtained from the National Archives...

Size at birth and coronary artery disease in a population with high birth weight.

BACKGROUND Epidemiologic studies suggest a link between fetal and childhood growth and later coronary artery disease (CAD). The influence of adult body size on the relation between birth size and CAD has not been thoroughly studied. OBJECTIVE We investigated the association between birth and adult sizes and CAD within a population with higher birth weight and a lower incidence of and mortalit...

The Relationship between Birth Weight, Insulin Resistance and Glucose Intolerance in 7 - Year Old Black Children

We investigated the relationship between glucose tolerance and birth weight in a group of 7-year-old black South Africans on whom longitudinal anthropometric data were available. Oral glucose tolerance tests (OGTT’s) were carried out on 152 subjects and inverse correlations were found between birth weight and the total amount of insulin secreted during the first 30 minutes (r= -0.19, p=0.04) an...

Glucose intolerance in Wisconsin's Hmong population.

Effect of maternal weight, adipokines, glucose intolerance and lipids on infant birth weight among women without gestational diabetes mellitus.

BACKGROUND The delivery of excess maternal nutrients to the fetus is known to increase the risk of macrosomia, even among infants of women without gestational diabetes mellitus. With the current obesity epidemic, maternal adiposity and its associated effects on circulating adipokines and inflammatory proteins may now have a greater impact on fetal growth. We sought to evaluate the independent e...